The phosphoproteomic landscape of the DNA damage response
Francesca Conte, Matthias Ostermaier, Juanjuan Wang, Christina Goss, Sergi Sayols, Jia-Xuan Chen, Vassilis Roukos, Frauke Graeter, Camilo A. Aponte-Santamaria, Katja Luck, Petra Beli
This study profiles the human phosphoproteome in response to eleven DNA damage agents, identifying core phosphorylation sites and DDR signatures, and links proteasome regulation to the DDR via UBE3A.
bioRxiv · May 13, 2026 · PreprintCell Biology