Author

K Chen

University of PittsburghPrimary ORCID profile (0009-0008-0553-6038 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

K CheniD1 paper · Sichuan University

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Buyun TianiD· 1 shared C Preszler· 1 shared Chaya Sussman· 1 shared Derek J. TayloriD· 1 shared Fan WangiD· 1 shared Fu‐Yu LiiD· 1 shared Guangfeng Zhang· 1 shared Jaime L. HookiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

Buyun TianORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multivalent Nanobodies for Potent and Broad Neutralization of Staphylococcus aureus Toxins

Y S Kim, Nicholas R. Walton, Wei Huang, Madison Lee, Yufei Xiang, Zhe Sang, Chaya Sussman, Sarah K. Moore, Derek J. Taylor, K Chen, Jaime L. Hook, John K. McCormick, Yi Shi

This paper develops multivalent nanobodies that neutralize multiple S. aureus toxins, showing potent activity in murine models of sepsis and pneumonia.

Nature Communications · May 20, 2026Peer-reviewedMicrobiology

Microglia surveillance is directed toward neuron activation during sustained intracortical microstimulation

C Preszler, Kevin C. Stieger, K Chen, Guangfeng Zhang, Takashi D.Y. Kozai

This study shows that 10-Hz intracortical microstimulation directs microglial surveillance toward activated neurons, revealing their role in modulating cortical circuits during early post-implantation.

Journal of Neural Engineering · Feb 1, 2026Peer-reviewedBioengineering

Targeting the host factor HGS-viral membrane protein interaction in coronavirus infection

Xubing Long, Rongrong Chen, Rong Bai, Buyun Tian, Yu Cao, K Chen, Fu‐Yu Li, Yiliang Wang, Yongjie Tang, Qi Yang, Liping Ma, Fan Wang, Maoge Zhou, Xianjie Qiu, Yongzhi Lu, , Zonghong Li

This study identifies HGS as a host factor critical for coronavirus infection and discovers RTB as a broad-spectrum antiviral by disrupting HGS-M protein interaction.

Journal of Clinical Investigation · Dec 16, 2025Peer-reviewedMicrobiology