Author

K. C. Hsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Calo· 1 shared C. A. Klebanoff· 1 shared C. S. Hackett· 1 shared D. Betel· 1 shared E. E. Er· 1 shared E. J. Brophy· 1 shared F. A. Dundar· 1 shared F. Yi· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Calo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

F. Yi, T. Cohen, N. Zimmerman, F. A. Dundar, P. Zumbo, R. Eltilib, E. J. Brophy, H. Arkin, J. Feucht, M. V. Gormally, C. S. Hackett, K. N. Kropp, I. Etxeberria, S. S. Chandran, J. H. Park, , C. A. Klebanoff

This study identifies FASLG expression patterns and shows that FAS-L/FAS auto-regulation governs CAR-T and CAR-NK cell persistence, enhancing antitumor efficacy when FAS is inhibited.

bioRxiv · Feb 26, 2024 · PreprintImmunology

Single-Cell Profiling Reveals a Naive-Memory Relationship between CD56bright and Adaptive Human Natural Killer Cells

M. K. Panjwani, S. Grassmann, R. Sottile, J.-B. Le Ludeuc, T. Kontopoulos, K. van der Ploeg, J. C. Sun, K. C. Hsu

The paper identifies a naive-memory relationship between CD56bright and adaptive human natural killer cells through phenotypic, transcriptional, and functional profiling.

bioRxiv · Sep 23, 2023 · PreprintImmunology

Cytotoxic lymphocytes use mechanosurveillance to target biophysical vulnerabilities in cancer

M. Tello-Lafoz, K. Srpan, J. Hu, Y. Romin, A. Calo, K. C. Hsu, J. Massague, M. Huse, E. E. Er

This study shows that cancer cells with increased MRTF signaling are more rigid and vulnerable to immune cells, revealing a mechanical aspect of immunosurveillance.

bioRxiv · Apr 21, 2020 · PreprintImmunology