Author

J. Massague

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Pe'er· 2 shared S. W. Lowe· 2 shared A. Barlas· 1 shared A. Calo· 1 shared A. Cercek· 1 shared A. Elghouayel· 1 shared A. Iavarone· 1 shared A. J. Dannenberg· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

D. Pe'er

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metastatic site influences driver gene function in pancreatic cancer

K. M. Tsanov, F. M. Barriga, Y.-J. Ho, D. Alonso-Curbelo, G. Livshits, R. P. Koche, T. Baslan, J. Simon, S. Tian, A. N. Wuest, W. Luan, J. E. Wilkinson, I. Masilionis, N. Dimitrova, C. A. Iacobuzio-Donahue, , S. W. Lowe

This study shows that metastatic site influences the function of driver genes like SMAD4 in pancreatic cancer, with organ-specific epigenetic states affecting tumor growth.

bioRxiv · Mar 17, 2024 · PreprintCancer Biology

Distinct tumor architectures for metastatic colonization of the brain

S. Gan, D. G. Macalinao, S. H. Shahoei, L. Tian, X. Jin, H. Basnet, J. T. Muller, P. Atri, E. Seffar, W. Chatila, A.-K. Hadjantonakis, N. Schultz, E. Brogi, T. A. Bale, D. Pe'er, J. Massague

This study compares the brain metastasis colonization strategies of triple-negative breast cancer and HER2+ breast cancer, revealing distinct tumor architectures and stromal interactions.

bioRxiv · Jan 27, 2023 · PreprintCancer Biology

Cytotoxic lymphocytes use mechanosurveillance to target biophysical vulnerabilities in cancer

M. Tello-Lafoz, K. Srpan, J. Hu, Y. Romin, A. Calo, K. C. Hsu, J. Massague, M. Huse, E. E. Er

This study shows that cancer cells with increased MRTF signaling are more rigid and vulnerable to immune cells, revealing a mechanical aspect of immunosurveillance.

bioRxiv · Apr 21, 2020 · PreprintImmunology

Anti-tumor effects of an Id antagonist with no acquired resistance

P. M. Wojnarowicz, M. G. Escalono, Y.-H. Huang, B. Desai, Y. Chin, R. Shah, S. Xu, O. Ouerfelli, R. K. Soni, J. Philip, D. C. Montrose, J. H. Healey, V. K. Rajasekhar, W. A. Garland, L. Norton, , R. Benezra

This study demonstrates that AGX51, an Id antagonist, effectively inhibits tumor growth in multiple cancer models without inducing acquired resistance.

bioRxiv · Jan 6, 2020 · PreprintCancer Biology

A rectal cancer model establishes a platform to study individual responses to chemoradiation

K. Ganesh, C. Wu, K. P. O'Rourke, M. Adileh, B. C. Szeglin, I. Wasserman, M. R. Marco, M. Shady, Y. Zheng, W. R. Karthaus, H. H. Won, S.-H. Choi, R. A. Pelossof, A. Barlas, E. Pappou, , J. J. Smith

This study develops a rectal cancer organoid model that mimics patient tumor responses to chemoradiation and metastasis in mice.

bioRxiv · May 22, 2019 · PreprintCancer Biology