K. Fukuzawa

Activity-specificity trade-off gives PI5P4Kβ a nucleotide preference to function as a GTP-sensing kinase.

This study identifies the TRNVF motif as responsible for PI5P4Kβ's GTP binding and extended specificity to ITP and XTP, showing how its GTP preference allows it to function as a GTP sensor despite low cellular concentrations of ITP and XTP.

An integrated approach unravels a crucial structural property for the function of the insect steroidogenic Halloween protein Noppera-bo

This paper determines the structure of the insect steroidogenic Halloween protein Noppera-bo and identifies a conserved residue critical for its function.