Author

K. G. Thakur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

R. Delipan· 2 shared R. P. Ringe· 2 shared R. Singh· 2 shared A. Bhardwaj· 1 shared A. Ganguly· 1 shared A. Kodesia· 1 shared A. Kumar· 1 shared A. Lee· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

R. Delipan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mutations in S2 subunit of SARS-CoV-2 Omicron spike strongly influence its conformation, fusogenicity and neutralization sensitivity

S. Kumar, R. Delipan, D. Chakraborty, K. Kanjo, R. Singh, N. Singh, S. Siddiqui, A. Tyagi, S. Jha, K. G. Thakur, R. Pandey, R. Varadarajan, R. P. Ringe

This study investigates how mutations in the S2 subunit of SARS-CoV-2 Omicron spike affect its structure, fusogenicity, and neutralization sensitivity.

bioRxiv · Mar 5, 2023Microbiology

UVC-based air disinfection system for rapid inactivation of SARS-CoV-2 present in the air

H. Garg, R. P. Ringe, S. Das, S. Parkash, B. Thakur, R. Delipan, A. Kumar, K. S. Kulkarni, K. Bansal, P. B. Patil, T. Alam, N. B. Balam, C. S. Meena, K. G. Thakur, A. Kumar, A. Kumar

This study demonstrates that UVC-based air disinfection systems can rapidly inactivate SARS-CoV-2 in aerosols by damaging its nucleic acids and altering its Spike protein conformation.

bioRxiv · Aug 2, 2022Microbiology

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

D. Chaudhary, M. Marzuki, A. Lee, R. Bouzeyen, A. Singh, T. P. Gosain, S. Kidwai, C. Grady, K. Tsotetsi, K. Chawla, F. Shihui, J. Lum, S. K. Gupta, N. Agarwal, L. Tsenova, , A. Singhal

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

bioRxiv · Sep 1, 2020 · PreprintMicrobiology

Structural characterization of Myxococcus xanthus MglC, a component of polarity control system, and its interactions with MglB

S. Kapoor, A. Kodesia, N. Kalidas, A. Ganguly, K. G. Thakur

The paper reports the crystal structure of MglC from Myxococcus xanthus, revealing its RLC7 fold and distinct structural features, and shows its interaction with MglB forming a 2:4 stoichiometric complex.

bioRxiv · Aug 27, 2020Biophysics

Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

A. Bhardwaj, D. Ghose, K. G. Thakur, D. Dutta

This study shows that Escherichia coli β-clamp inhibits DNA polymerase I nick translation but promotes ligation during Okazaki fragment maturation.

bioRxiv · Jun 14, 2018Biochemistry