Author

R. G. H. Lindeboom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

K. B. Meyer· 3 shared M. Haniffa· 3 shared M. R. Clatworthy· 3 shared Z. K. Tuong· 3 shared C. Suo· 2 shared E. Dann· 2 shared K. Polanski· 2 shared M. Yoshida· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

K. B. Meyer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Early human lung immune cell development and its role in epithelial cell fate

J. L. Barnes, P. He, M. Yoshida, K. B. Worlock, R. G. H. Lindeboom, C. Suo, J. P. Pett, A. Wilbrey-Clark, E. Dann, L. Mamanova, L. Richardson, A. J. Oliver, A. L. Pennycuick, J. Allen-Hyttinen, I. T. Herczeg, , M. Z. Nikolic

The paper profiles lung immune cells during development using scRNAseq and identifies IL-1β's role in driving epithelial progenitor differentiation.

bioRxiv · Dec 13, 2022Immunology

Dandelion utilizes single cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

C. Suo, K. Polanski, E. Dann, R. G. H. Lindeboom, R. Vilarrasa Blasi, R. Vento-Tormo, M. Haniffa, K. B. Meyer, L. M. Dratva, Z. K. Tuong, M. R. Clatworthy, S. Teichmann

Dandelion improves V(D)J analysis in scVDJ-seq data, enabling better lineage commitment predictions and insights into lymphocyte development.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Obesity associated with attenuated tissue immune cell responses in COVID-19

S. A. Guo, G. S. Bowyer, J. R. Ferdinand, M. Maes, Z. K. Tuong, E. Gilman, M. Liao, R. G. H. Lindeboom, M. Yoshida, K. Worlock, H. Gopee, E. Stephenson, P. A. Lyons, K. G. C. Smith, M. Haniffa, , M. R. Clatworthy

The paper finds that obesity is associated with reduced immune and inflammatory responses in COVID-19 patients, including lower expression of IFN and IFNγ response genes in lung and blood cells.

bioRxiv · Jan 14, 2022 · PreprintImmunology

RNF43 truncating mutations mediate a tumour suppressor-to-oncogene switch to drive niche-independent self-renewal in cancer

M. Spit, N. Fenderico, I. Jordens, T. Radaszkiewicz, R. G. H. Lindeboom, J. M. Bugter, L. Ootes, M. van Osch, E. Janssen, K. E. Boonekamp, K. Hanakova, D. Potesil, Z. Zdrahal, S. F. Boj, J. P. Medema, , M. M. Maurice

This study identifies RNF43 truncating mutations that switch from tumor suppressor to oncogene, enabling niche-independent self-renewal in cancer and resistance to anti-Wnt therapy.

bioRxiv · Sep 1, 2019Cancer Biology