Author

K. J. Butay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

M. J. Borgnia· 2 shared C. Z. Chen· 1 shared D. Esposito· 1 shared D. Li· 1 shared H. Guterres· 1 shared H. J. Kwon· 1 shared H. Ren· 1 shared H. Xie· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

M. J. Borgnia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2

Y. Suo, N. J. Wright, H. Guterres, J. G. Fedor, K. J. Butay, M. J. Borgnia, W. Im, S.-Y. Lee

The paper presents cryo-EM structures of OCT1 and OCT2 in different states and combines them with functional experiments to reveal principles of organic cation recognition and the alternating access mechanism.

bioRxiv · Mar 15, 2023Biophysics

Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease

M. N. Frazier, I. M. Wilson, J. M. Krahn, K. J. Butay, L. B. Dillard, M. J. N. Borgnia, R. E. Stanley

This study determines the structure of SARS-CoV-2 Nsp15 bound to dsRNA, revealing a base-flipping mechanism for dsRNA cleavage and its ability to process both ss- and dsRNA.

bioRxiv · Mar 2, 2022Biochemistry

Camel nanobodies broadly neutralize SARS-CoV-2 variants

J. Hong, H. J. Kwon, R. Cachau, C. Z. Chen, K. J. Butay, Z. Duan, D. Li, H. Ren, T. Liang, J. Zhu, V. P. Dandey, N. P. Martin, D. Esposito, U. Ortega-Rodriguez, M. Xu, , M. Ho

The paper isolates two camel nanobodies that broadly neutralize SARS-CoV-2 and its variants, showing therapeutic potential in mice.

bioRxiv · Oct 27, 2021Immunology