Author

K. Kishimoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Hoffmann· 1 shared A. Ohno· 1 shared A. S. Meyer· 1 shared A. Ulla· 1 shared A. Zuniga Munoz· 1 shared C. Wilder· 1 shared D. Lefaudeux· 1 shared H. Nagano· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Hoffmann

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2 papers

Recent·Most cited

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

C. Wilder, D. Lefaudeux, R. Mathenge, K. Kishimoto, A. Zuniga Munoz, M. A. Nguyen, A. S. Meyer, Q. J. Cheng, A. Hoffmann

The paper shows high-dose IFN-β activates a pro-inflammatory gene program through a stimulus-contingent positive feedback loop in ISGF3, unlike IFN-λ3.

bioRxiv · Aug 11, 2022Immunology

Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

A. Ohno, N. Maita, T. Tabata, H. Nagano, K. Arita, M. Ariyoshi, T. Uchida, R. Nakao, A. Ulla, K. Sugiura, K. Kishimoto, S. Teshima-Kondo, Y. Okumura, T. Nikawa

The paper determines the crystal structure of human MSPL bound to an inhibitor, revealing key residues involved in substrate recognition and providing a homology model for TMPRSS2.

bioRxiv · Jun 12, 2020Biophysics