Author

K. Arita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:protein structure prediction· 3 Organism:mouse· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Nishiyama· 3 shared M. Nakanishi· 3 shared Y. Chiba· 3 shared H. Onoda· 2 shared S. Yoshimi· 2 shared T. Konuma· 2 shared A. Kikuchi· 1 shared A. Ohno· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

A. Nishiyama

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3

N. Shiraishi, T. Konuma, Y. Chiba, S. Hokazono, N. Nakamura, M. H. Islam, M. Nakanishi, A. Nishiyama, K. Arita

This study compares the structural and functional differences between human and mouse DPPA3 in binding to UHRF1 PHD finger, showing weaker human DPPA3 binding and reduced inhibition of UHRF1 chromatin binding.

bioRxiv · Jan 11, 2024Biochemistry

Structural basis for activation of DNMT1

A. Kikuchi, H. Onoda, K. Yamaguchi, S. Kori, S. Matsuzawa, Y. Chiba, S. Tanimoto, S. Yoshimi, H. Sato, A. Yamagata, M. Shirouzu, N. Adachi, J. Sharif, H. Koseki, A. Nishiyama, , K. Arita

This study determines the cryo-EM structure of DNMT1 bound to hemimethylated DNA and ubiquitinated histone H3, revealing a mechanism for its activation.

bioRxiv · Jun 16, 2022Biochemistry

Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger

K. Hata, N. Kobayashi, K. Sugimura, W. Qin, D. Haxholli, Y. Chiba, S. Yoshimi, G. Hayashi, H. Onoda, T. Ikegami, C. B. Mulholland, A. Nishiyama, M. Nakanishi, H. Leonhardt, T. Konuma, K. Arita

This study determines the structure of the mouse UHRF1 PHD domain complexed with DPPA3, revealing how DPPA3 inhibits UHRF1 chromatin localization through unique interactions.

bioRxiv · Jun 14, 2022Biochemistry

Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

A. Ohno, N. Maita, T. Tabata, H. Nagano, K. Arita, M. Ariyoshi, T. Uchida, R. Nakao, A. Ulla, K. Sugiura, K. Kishimoto, S. Teshima-Kondo, Y. Okumura, T. Nikawa

The paper determines the crystal structure of human MSPL bound to an inhibitor, revealing key residues involved in substrate recognition and providing a homology model for TMPRSS2.

bioRxiv · Jun 12, 2020Biophysics