Author

K. Sugiura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:dimensionality reduction· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1

Frequent Co-Authors

K. Fujita· 2 shared R. Heintzmann· 2 shared T. Kubo· 2 shared T. Nagai· 2 shared A. K. Rustgi· 1 shared A. Ohno· 1 shared A. Ulla· 1 shared C. Loebel· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

K. Fujita

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Time-deterministic cryo-optical microscopy

M. Yamanaka, K. Tsuji, Y. Kumamoto, S. Tamura, W. Miyamura, T. Kubo, K. Mizushima, K. Kono, H. Hirano, K. Sugiura, S.-i. Fukushima, T. Kunimoto, K. Nishida, K. Mochizuki, Y. Harada, , K. Fujita

The paper introduces a technique to rapidly freeze biological systems during optical observation, enabling detailed time-specific analysis of cellular dynamics at high spatial resolution.

bioRxiv · Aug 1, 2023 · PreprintBiophysics

Selective plane activation structured illumination microscopy

K. Temma, R. Oketani, T. Kubo, K. Bando, S. Maeda, K. Sugiura, T. Matsuda, R. Heintzmann, T. Kaminishi, K. Fukuda, M. Hamasaki, T. Nagai, K. Fujita

This study improves structured illumination microscopy by using selective plane illumination and photoswitchable proteins to eliminate out-of-focus background, enabling high-resolution imaging of volumetric samples.

bioRxiv · Jun 19, 2023Biophysics

Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma 3D organoids and identify matrix-activated therapeutic targets

R. Cruz-Acuna, S. W. Kariuki, K. Sugiura, C. Loebel, T. Karakasheva, J. T. Gabre, J. A. Burdick, A. K. Rustgi

The paper develops a hydrogel platform to study matrix mechanics in EAC organoids and identifies therapeutic targets for ECM stiffness.

bioRxiv · Nov 13, 2022 · PreprintBioengineering

Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

A. Ohno, N. Maita, T. Tabata, H. Nagano, K. Arita, M. Ariyoshi, T. Uchida, R. Nakao, A. Ulla, K. Sugiura, K. Kishimoto, S. Teshima-Kondo, Y. Okumura, T. Nikawa

The paper determines the crystal structure of human MSPL bound to an inhibitor, revealing key residues involved in substrate recognition and providing a homology model for TMPRSS2.

bioRxiv · Jun 12, 2020Biophysics