Author

M. A. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Hoffmann· 1 shared A. S. Meyer· 1 shared A. Zuniga Munoz· 1 shared C. A. Schiffer· 1 shared C. Wilder· 1 shared D. Bauer· 1 shared D. Lefaudeux· 1 shared D. S. Loustaunau· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Hoffmann

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Author profile →

2 papers

Recent·Most cited

Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

J. M. Lee, J. Zeng, P. Liu, M. A. Nguyen, D. S. Loustaunau, D. Bauer, N. K. Yilmaz, S. Wolfe, C. A. Schiffer

This study develops stabilized Cas-embedded base editors (sCE_CBEs) that enable efficient and accurate C-to-T editing with minimal off-target effects in hematopoietic stem and progenitor cells.

bioRxiv · Feb 8, 2024 · PreprintBiochemistry

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

C. Wilder, D. Lefaudeux, R. Mathenge, K. Kishimoto, A. Zuniga Munoz, M. A. Nguyen, A. S. Meyer, Q. J. Cheng, A. Hoffmann

The paper shows high-dose IFN-β activates a pro-inflammatory gene program through a stimulus-contingent positive feedback loop in ISGF3, unlike IFN-λ3.

bioRxiv · Aug 11, 2022Immunology