Author
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2 papers
Recent·Most cited
K. M. Schukken, Y. Zhu, P. L. Bakker, L. Harkema, S. A. Youssef, A. de Bruin, F. Foijer
This study shows that acute systemic loss of Mad2 in adult mice causes intestinal atrophy, weight loss, and death within 10 days due to high-grade CIN, with minimal effects on other tissues.
bioRxiv · Dec 3, 2020Cancer Biology
K. M. Schukken, Y.-C. Lin, M. Schubert, S. F. Preuss, J. E. Simon, H. van den Bos, Z. Storchova, H. Bastians, D. C. J. Spierings, F. Foijer
The paper identifies synergistic toxicity between microtubule dynamics alteration and SAC inhibition in aneuploid cells.
bioRxiv · Jul 22, 2019Cancer Biology