Author

H. van den Bos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. C. J. Spierings· 3 shared F. Foijer· 3 shared A. Adamska· 1 shared A. de Bruin· 1 shared A. Manas· 1 shared A. Seger· 1 shared A. Villunger· 1 shared B. Westendorp· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

D. C. J. Spierings

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clinically-relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance

A. Manas, K. Aaltonen, N. Anderson, K. Hansson, A. Adamska, A. Seger, H. Yasui, H. van den Bos, K. Radke, J. Esfandyari, M. S. Bhave, J. Karlsson, D. C. J. Spierings, F. Foijer, D. Gisselsson, D. Bexell

The paper applies a clinically-relevant chemotherapy regimen to neuroblastoma PDX models to identify transcriptional patterns and mechanisms of chemoresistance.

bioRxiv · Apr 1, 2022Cancer Biology

PIDDosome-induced p53-activation for ploidy restriction facilitates hepatocarcinogenesis

V. C. Sladky, K. Knapp, T. G. Szabo, L. Bongiovanni, H. van den Bos, D. C. J. Spierings, B. Westendorp, T. Stojakovic, H. Scharnagl, G. Timelthaler, K. Tsuchia, M. Pinter, F. Foijer, A. de Bruin, T. Reiberger, , A. Villunger

This study shows that PIDDosome-mediated ploidy restriction prevents hepatocellular carcinoma by reducing tumor burden and that low ploidy predicts poor survival in HCC patients.

bioRxiv · May 13, 2020 · PreprintCancer Biology

Altering microtubule dynamics is synergistically toxic with inhibition of the spindle checkpoint

K. M. Schukken, Y.-C. Lin, M. Schubert, S. F. Preuss, J. E. Simon, H. van den Bos, Z. Storchova, H. Bastians, D. C. J. Spierings, F. Foijer

The paper identifies synergistic toxicity between microtubule dynamics alteration and SAC inhibition in aneuploid cells.

bioRxiv · Jul 22, 2019Cancer Biology