Author

P. L. Bakker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Foijer· 3 shared A. de Bruin· 2 shared B. Bakker· 2 shared D. C. J. Spierings· 2 shared S. A. Youssef· 2 shared A. Damaskou· 1 shared A. E. Tijhuis· 1 shared A. Strong· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

F. Foijer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

M. Schubert, C. Hong, L. J. Jilderda, M. Requesens-Rueda, A. E. Tijhuis, J. E. Simon, P. L. Bakker, J. Cooper, A. Damaskou, R. Wardenaar, B. Bakker, S. Gupta, A. van den Brink, L. Andrade-Ruiz, M. H. Koster, , F. Foijer

The paper identifies Stat1 inactivation as a mechanism by which aneuploid cancers evade immune surveillance in mice and humans.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology

Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice

K. M. Schukken, Y. Zhu, P. L. Bakker, L. Harkema, S. A. Youssef, A. de Bruin, F. Foijer

This study shows that acute systemic loss of Mad2 in adult mice causes intestinal atrophy, weight loss, and death within 10 days due to high-grade CIN, with minimal effects on other tissues.

bioRxiv · Dec 3, 2020Cancer Biology

Single cell DNA sequencing reveals distinct molecular types of basal cell carcinoma with unique transcriptome features

B. Bakker, J. Terra, L. Zhou, E. Racz, S. Paljic, J. Garcia-Martinez, V. Oliveira, P. L. Bakker, D. C. J. Spierings, M. F. Jonkman, F. Foijer

This study uses single-cell DNA sequencing to identify distinct molecular types of basal cell carcinoma based on karyotype heterogeneity and associated transcriptome features.

bioRxiv · Dec 11, 2018 · PreprintCancer Biology