K. P. M. van Kessel

This study shows that C1r2s2 proteases stabilize C1q binding to surface-bound IgG, with subclass-specific effects and improved phagocytosis with hexamer-enhanced IgGs.

This study shows Staphylococcal protein A inhibits IgG hexamer formation, blocking complement activation, but IgG3 can still induce complement activation despite SpA.

This study evaluates CHIPS as a therapeutic agent for inflammation, showing promise in mice but safety concerns in humans due to pre-existing antibodies.

This study shows SSL13 activates neutrophils through FPR2, acting as a chemoattractant and inducer of degranulation and oxidative burst, differing from other SSLs that inhibit immune responses.