Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
N. Bobba-Alves, G. Sturm, J. Lin, S. A. Ware, K. R. Karan, A. S. Monzel, C. Bris, V. Procaccio, G. Lenaers, A. Higgins-Chen, M. Levine, S. Horvath, B. S. Santhanam, B. A. Kaufman, M. Hirano, , M. Picard
The paper shows chronic glucocorticoid exposure increases cellular energy expenditure and accelerates aging in human fibroblasts.
Psychoneuroendocrinology · Sep 1, 2023Peer-reviewedCell Biology
K. R. Karan, C. Trumpff, M. Cross, K. M. Englestad, A. L. Marsland, P. McGuire, M. Hirano, M. Picard
This study examines cytokine responses and glucocorticoid sensitivity in leukocytes from patients with mitochondrial DNA defects, finding reduced IL-6 and IL-1β responses to LPS in those with mtDNA deletions.
bioRxiv · Dec 13, 2021Immunology
G. Sturm, K. R. Karan, A. Monzel, B. S. Santhanham, T. Taivassalo, C. Bris, S. A. Duplaga, M. Cross, A. Towheed, A. Higgins-Chen, M. J. McManus, A. Cardenas, J. Lin, E. S. Epel, S. Rahman, , M. Picard
The paper shows that OxPhos dysfunction leads to hypermetabolism and reduced lifespan in cells and mitochondrial disease patients.
bioRxiv · Nov 29, 2021Cell Biology
G. Sturm, A. S. Monzel, K. R. Karan, J. Michelson, S. A. Ware, A. Cardenas, J. Lin, C. Bris, B. Santhanam, M. P. Murphy, M. E. Levine, S. Horvath, D. W. Belsky, S. Wang, V. Procaccio, , M. Picard
The paper presents a longitudinal multi-omics dataset of human fibroblasts with mitochondrial perturbations to study aging mechanisms and bioenergetics.
bioRxiv · Nov 12, 2021Cell Biology
S. Rausser, C. Trumpff, M. A. McGill, A. Junker, W. Wang, S.-H. Ho, A. Mitchell, K. R. Karan, C. Monk, S. C. Segerstrom, R. G. Reed, M. Picard
The paper quantifies mitochondrial features in purified human immune cell subtypes and mixed cell populations, revealing age- and sex-related differences and confounding effects of cell type distribution and platelets.
bioRxiv · Oct 16, 2020Cell Biology