Author

G. Lenaers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:metabolism & bioenergetics· 2

Frequent Co-Authors

V. Procaccio· 3 shared A. Higgins-Chen· 2 shared B. A. Kaufman· 2 shared C. Bris· 2 shared E. S. Epel· 2 shared G. Sturm· 2 shared J. Lin· 2 shared K. R. Karan· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

V. Procaccio

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In-depth study of MPV17: a molecular travel unveiling a mitochondrial calcium regulation function

S. Meurant, I. Amato, L. Mauclet, M. Dieu, A. Chevrollier, B. Ledoux, M. Caruso, G. Lenaers, T. Arnould, P. Renard

This study identifies MPV17 as a regulator of mitochondrial calcium and oxidative stress, showing its role in preventing mtDNA degradation through interactions with the MICOS complex.

bioRxiv · Apr 12, 2024 · PreprintCell Biology

Cellular Allostatic Load is linked to Increased Energy Expenditure and Accelerated Biological Aging

N. Bobba-Alves, G. Sturm, J. Lin, S. A. Ware, K. R. Karan, A. S. Monzel, C. Bris, V. Procaccio, G. Lenaers, A. Higgins-Chen, M. Levine, S. Horvath, B. S. Santhanam, B. A. Kaufman, M. Hirano, , M. Picard

The paper shows chronic glucocorticoid exposure increases cellular energy expenditure and accelerates aging in human fibroblasts.

Psychoneuroendocrinology · Sep 1, 2023Peer-reviewedCell Biology

OxPhos Dysfunction Causes Hypermetabolism and Reduces Lifespan in Cells and in Patients with Mitochondrial Diseases

G. Sturm, K. R. Karan, A. Monzel, B. S. Santhanham, T. Taivassalo, C. Bris, S. A. Duplaga, M. Cross, A. Towheed, A. Higgins-Chen, M. J. McManus, A. Cardenas, J. Lin, E. S. Epel, S. Rahman, , M. Picard

The paper shows that OxPhos dysfunction leads to hypermetabolism and reduced lifespan in cells and mitochondrial disease patients.

bioRxiv · Nov 29, 2021Cell Biology

Nicotinamide Deficiency In Primary Open-Angle Glaucoma

J. Kouassi Nzoughet, J. M. Chao de la Barca, K. Guehlouz, S. Leruez, L. Coulbault, S. Allouche, C. Bocca, J. Muller, P. Amati-Bonneau, P. Gohier, D. Bonneau, G. Simard, D. Milea, G. Lenaers, V. Procaccio, P. Reynier

This study finds lower plasma nicotinamide levels in primary open-angle glaucoma patients compared to controls, suggesting potential therapeutic implications.

bioRxiv · Mar 18, 2019Biochemistry