Author

A. S. Monzel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Assay:DNA methylation· 2

Frequent Co-Authors

M. Picard· 4 shared B. A. Kaufman· 3 shared M. Hirano· 3 shared A. L. Marsland· 2 shared C. Bris· 2 shared C. Trumpff· 2 shared D. W. Belsky· 2 shared G. Sturm· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCell Biology

M. Picard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress

Q. Huang, A. S. Monzel, S. Rausser, R. Haahr, C. E. Indik, M. J. Savin, N. Bobba-Alves, C. C. Liu, J. Devine, E. Thompson, C. Kelly, M. S. Kurade, J. Michelson, S. Li, K. Engelstad, , C. Trumpff

This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.

bioRxiv · Apr 19, 2024 · PreprintPhysiology

Cellular Allostatic Load is linked to Increased Energy Expenditure and Accelerated Biological Aging

N. Bobba-Alves, G. Sturm, J. Lin, S. A. Ware, K. R. Karan, A. S. Monzel, C. Bris, V. Procaccio, G. Lenaers, A. Higgins-Chen, M. Levine, S. Horvath, B. S. Santhanam, B. A. Kaufman, M. Hirano, , M. Picard

The paper shows chronic glucocorticoid exposure increases cellular energy expenditure and accelerates aging in human fibroblasts.

Psychoneuroendocrinology · Sep 1, 2023Peer-reviewedCell Biology

Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transduction

S. Basarrate, A. S. Monzel, J. Smith, A. L. Marsland, C. Trumpff, M. Picard

This study maps glucocorticoid and adrenergic receptor expression across human organs, showing tissue-specific patterns and their link to mitochondrial pathways in stress responses.

bioRxiv · Dec 29, 2022Cell Biology

A Multi-Omics and Bioenergetics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations

G. Sturm, A. S. Monzel, K. R. Karan, J. Michelson, S. A. Ware, A. Cardenas, J. Lin, C. Bris, B. Santhanam, M. P. Murphy, M. E. Levine, S. Horvath, D. W. Belsky, S. Wang, V. Procaccio, , M. Picard

The paper presents a longitudinal multi-omics dataset of human fibroblasts with mitochondrial perturbations to study aging mechanisms and bioenergetics.

bioRxiv · Nov 12, 2021Cell Biology

Machine learning-assisted neurotoxicity prediction in human midbrain organoids

A. S. Monzel, K. Hemmer, T. Kaoma Mukendi, P. Lucarelli, I. Rosety, A. Zagare, S. Bolognin, P. Antony, S. L. Nickels, R. Krueger, F. Azuaje, J. C. Schwamborn

The paper develops a midbrain organoid system to model Parkinson's disease and introduces a machine learning pipeline for neurotoxicity prediction using high-content imaging data.

bioRxiv · Sep 19, 2019Pharmacology & Toxicology