Novel adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments
Y.-T. Wang, A. Trzeciak, W. S. Rojas, P. Saavedra, Y.-T. Chen, R. Chirayil, J. I. Etchegaray, C. D. Lucas, D. J. Puleston, K. R. Keshari, J. S. A. Perry
This study identifies two macrophage states induced by chronic hypoxia that enhance efferocytosis through metabolic and transcriptional adaptations.
bioRxiv · Aug 4, 2022Immunology