Author

K. Thedieck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. M. Heberle· 2 shared C. A. Opitz· 2 shared M. Kwiatkowski· 2 shared A. Hofer· 1 shared A. Kopach· 1 shared A. Rambold· 1 shared A. Reintjes· 1 shared A. Teleman· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

A. M. Heberle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Automated liquid handling extraction and rapid quantification of underivatized amino acids and tryptophan metabolites from human serum and plasma using dual-column U(H)PLC-MRM-MS and its application to prostate cancer study.

T. Kipura, M. Hotze, A. Hofer, A.-S. Egger, L. E. Timpen, C. Opitz, P. Townsend, L. Gethings, K. Thedieck, M. Kwiatkowski

The paper develops an automated workflow and dual-column U(H)PLC-MRM-MS method to rapidly quantify amino acids and tryptophan metabolites in human serum and plasma, applied to a prostate cancer study to identify biomarkers.

Metabolites · Jun 30, 2024Peer-reviewedBiochemistry

LRBA balances antigen presentation and T-cell responses via autophagy through the binding to PIK3R4 and FYCO1

E. Sindram, M. C. Deau, L. A. Ligeon, P. Sanchez-Martin, S. Nestel, S. Jung, S. Ruf, P. Mishra, M. Proietti, S. Guenther, K. Thedieck, E. Roussa, A. Rambold, C. Muenz, C. Kraft, , L. Gamez-Diaz

This study identifies LRBA's role in balancing antigen presentation and T-cell responses by interacting with PIK3R4 and FYCO1 to regulate autophagy.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Comparative assessment of quantification methods for tumor tissue phosphoproteomics

Y. Zhang, B. Dreyer, N. Govorukhina, A. M. Heberle, S. Koncarevic, C. Krisp, C. A. Opitz, P. Pfander, R. Bischoff, H. Schluter, M. Kwiatkowski, K. Thedieck, P. Horvatovich

This study compares quantification methods for tumor tissue phosphoproteomics and finds TMT offers highest precision, spike-in-SILAC balances features best, and LFQ provides most identifications.

bioRxiv · Feb 7, 2022Biochemistry

G3BP1 tethers the TSC complex to lysosomes and suppresses mTORC1 in the absence of stress granules

M. T. Prentzell, U. Rehbein, M. Cadena Sandoval, A.-S. De Meulemeester, R. Baumeister, L. Brohee, B. Berdel, M. Bockwoldt, B. Carroll, A. von Deimling, C. Demetriades, G. Figlia, A. M. Heberle, I. Heiland, B. Holzwarth, , K. Thedieck

This paper shows G3BP1 anchors the TSC complex to lysosomes to suppress mTORC1 signaling without stress granules, and inhibits mTORC1-driven cancer and neuronal issues.

bioRxiv · Apr 16, 2020Cell Biology