Author

G. Al-Atrash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:clinical cohort / trial· 1 Approach:deep learning· 1

Frequent Co-Authors

G. Garcia-Manero· 3 shared F. Ma· 2 shared G. Montalban-Bravo· 2 shared H. Yang· 2 shared I. Ganan-Gomez· 2 shared J. J. Rodriguez-Sevilla· 2 shared K. Takahashi· 2 shared N. Thongon· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

G. Garcia-Manero

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Author profile →

3 papers

Recent·Most cited

IL-1B-mediated inflammatory signaling drives ineffective erythropoiesis in early-stage myelodysplastic syndromes

V. Adema, I. Ganan-Gomez, F. Ma, J. J. Rodriguez-Sevilla, K. Chien, H. Yang, N. Thongon, R. Kanagal-Shamanna, S. Loghavi, G. Montalban-Bravo, D. Hammond, Y. Gu, R. Tan, L. Tan, P. Lorenzi, , S. Colla

This study shows that IL-1B-mediated inflammation drives ineffective erythropoiesis in early-stage MDS and that canakinumab can reduce transfusion dependence in patients with DNMT3A and TET2 mutations.

bioRxiv · Sep 28, 2023 · PreprintCancer Biology

Targeting MCL1-driven anti-apoptotic pathways to overcome hypomethylating agent resistance in RAS-mutated chronic myelomonocytic leukemia

G. Montalban-Bravo, F. Ma, N. Thongon, H. Yang, I. Ganan-Gomez, J. J. Rodriguez-Sevilla, V. Adema, B. Wildeman, P. P. Lockyer, Y. J. Kim, T. Tanaka, F. Darbaniyan, S. Pancholy, G. Zhang, G. Al-Atrash, , S. Colla

This study identifies MCL1 as a survival factor in RAS-mutated CMML, explaining resistance to BCL2 inhibitors and suggesting new therapeutic targets.

bioRxiv · Apr 7, 2023 · PreprintCancer Biology

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

H. A. Abbas, D. Hao, K. Tomczak, P. Baroodia, J. Im, P. K. Reville, Z. Alaniz, W. Wang, R. Wang, F. Wang, G. Al-Atrash, K. Takahashi, J. Ning, M. Ding, J. Matthews, , A. Futreal

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

bioRxiv · Sep 3, 2020Cancer Biology