Author

K. W. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

B.-G. Jeong· 1 shared D.-W. Bae· 1 shared E.-K. Kim· 1 shared G. C. McAlister· 1 shared G. S. Lee· 1 shared H.-S. Yim· 1 shared J. Coon· 1 shared J. D. Hinkle· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

B.-G. Jeong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Boosting the Sensitivity of Quantitative Single-Cell Proteomics with Activated Ion-Tandem Mass Tags (AI-TMT)

T. Peters-Clarke, Y. Liang, K. L. Mertz, K. W. Lee, M. S. Westphall, J. D. Hinkle, G. C. McAlister, J. E. P. Syka, R. T. Kelly, J. Coon

This paper introduces AI-TMT, a method enhancing single-cell proteomics sensitivity by improving reporter ion generation, resulting in higher signal and faster analysis.

bioRxiv · Feb 24, 2024 · PreprintBiochemistry

An alphacoronavirus polymerase structure reveals conserved co-factor functions

T. K. Anderson, P. J. Hoferle, K. W. Lee, J. J. Coon, R. N. Kirchdoerfer

This paper determines the structure of an alphacoronavirus polymerase complex and identifies conserved cofactor interactions important for antiviral drug development.

bioRxiv · Mar 15, 2023 · PreprintBiochemistry

Temperature-responsive structural reversibility of FGF21 and structure-based design of its variant with enhanced potency

Y.-E. Jung, K. W. Lee, J. H. Cho, D.-W. Bae, B.-G. Jeong, Y.-J. Jung, Y. J. An, K. Kim, G. S. Lee, L.-W. Kang, J. H. Moon, J.-H. Lee, E.-K. Kim, H.-S. Yim, S.-S. Cha

This study investigates the thermal behavior of FGF21 and designs a variant with enhanced therapeutic potency through structural analysis and mutagenesis.

bioRxiv · Nov 16, 2021 · PreprintBiochemistry