Author

K. Wen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Alimova· 1 shared A. C. Zhu· 1 shared A. Katz· 1 shared A. Sanchez Castillo· 1 shared B. Gavrilov· 1 shared C. He· 1 shared C. Sepich-Poore· 1 shared E. Schmitt· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiophysics

A. Alimova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Rare Monoclonal Antibody Discovery Based on Indirect Competitive Screening of Single Hapten-specific Rabbit Antibody Secreting Cell

Y. Li, P. Li, Y. Ke, X. Yu, W. Yu, K. Wen, J. Shen, z. wang

This paper introduces a method to discover rare rabbit monoclonal antibodies against small molecules using an indirect competitive screening approach, resulting in a highly stable antibody with exceptional halophilic properties.

The Analyst · Jan 1, 2022Peer-reviewedBiochemistry

The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation

C. Sepich-Poore, Z. Zheng, E. Schmitt, K. Wen, Z. S. Zhang, X.-L. Cui, Q. Dai, A. C. Zhu, L. Zhang, A. Sanchez Castillo, X. Zhuang, C. He, S. Nachtergaele

This paper identifies the METTL5-TRMT112 complex as the methyltransferase responsible for m6A modification at 18S rRNA, linking it to metabolism and development.

bioRxiv · May 18, 2021Biochemistry

Human Embryonic Stem Cell-derived Lung Organoids: a Model for SARS-CoV-2 Infection and Drug Test

R. Pei, J. Feng, Y. Zhang, H. Sun, L. Li, X. Yang, J. He, S. Xiao, J. Xiong, Y. Lin, K. Wen, H. Zhou, J. Chen, Z. Rong, X. Chen

This study shows that human lung organoids can model SARS-CoV-2 infection and drug response, revealing virus targets and effective antiviral treatment.

bioRxiv · Aug 10, 2020 · PreprintMicrobiology

Structural characterization of the PCV2d genotype at 3.3 A resolution reveals differences to PCV2a and PCV2b genotypes, a tetranucleotide, and an N-terminus near the icosahedral 3-fold axes

R. Khayat, K. Wen, A. Alimova, B. Gavrilov, A. Katz, J. M. Galarza, P. Gottlieb

The paper determines the 3.3 Å cryo-EM structure of PCV2d VLP and compares it to PCV2a and PCV2b, identifying structural changes and amino acid substitutions that may relate to vaccine response.

bioRxiv · Apr 19, 2019Biophysics