AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
Apolonia Gardner, Shuai Wang, Adam Daniels, Dan Dan Li, Christine C. Wu, Lucas Lin, Christin M. Hong, Sophia R. Zhao, Richard T. Born, Kamil Kruczek, Genevieve Weist, Laura Barrio Real, Joan Wicks, Mohamad Nayal, Ashley Carter, , Constance L. Cepko
This paper tests AAV8/Best1-Nrf2 gene therapy in rodent models of oxidative stress, showing protection of retinal cells and preservation of visual function.
Molecular Therapy · Feb 6, 2026Peer-reviewedPharmacology & Toxicology