Hua Tang

Integrative analysis reveals extensive interactions among C2H2 zinc finger proteins at chromatin loop anchors

The paper identifies extensive interactions among C2H2 zinc finger proteins at chromatin loop anchors using ChIP-seq, interactome data, and chromatin interaction maps.

An Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition

This paper describes an automated AC-MS platform with DIA-MS for efficient kinase profiling and inhibitor selectivity assessment.

Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

This study identifies ZBTB48 as a regulator of FTO's substrate selectivity by facilitating its binding to m6A/m6Am-containing RNAs, affecting RNA decay and cancer cell growth.

SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs

This study identifies SARS-CoV-2 N protein interactions with host proteins and mRNAs, showing it attenuates stress granule formation and alters gene expression.

Joint Genotype- and Ancestry-based Genome-wide Association Studies in Admixed Populations

This paper introduces a method that combines genotype and ancestry data in GWAS for admixed populations, improving detection of causal mutations by balancing power and precision.

Increasing the Efficiency of Genome-wide Association Mapping via Hidden Markov Models

This paper introduces a hidden Markov model-based method to improve genome-wide association study power by reducing background noise and detecting causal SNPs with non-additive or unknown allelic effects.