Author

Karen Chan

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alexandra SchureriD· 1 shared Aly KarsaniD· 1 shared Amber LouwagieiD· 1 shared Brenda Ma· 1 shared Christopher C. OakesiD· 1 shared Debajeet GhoshiD· 1 shared Diana Lin· 1 shared Fabiana PernaiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alexandra SchurerORCID

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2 papers

Recent·Most cited

LncRNA-mediated organization of oncogenic chromatin state is a targetable vulnerability in leukemia

Ly Vu, Zhen Jin, Brenda Ma, Karen Chan, Diana Lin, Debajeet Ghosh, Amber Louwagie, Luke Saville, Joanne Liani Chandra, Yilin Liu, Zongmin Liu, Leo Escano, Sandra Spencer Miko, Se Wing Grace Cheng, Priscila Elias Ferreira Stricker, , Pieter R. Cullis

This study identifies PAN3-AS1 as an oncogenic lncRNA in AML, shows its role in chromatin organization, and demonstrates RNA-targeting LNP therapy to reduce leukemia burden.

bioRxiv · Aug 11, 2026 · PreprintCancer Biology

Different capsid-binding patterns of the β-herpesvirus-specific tegument protein pp150 (pM32/pUL32) in murine and human cytomegaloviruses

Wei Liu, Xinghong Dai, Jonathan Jih, Karen Chan, Phong Trang, Xuekui Yu, Rilwan Balogun, Ye Mei, Fenyong Liu, Z. Hong Zhou

This study compares the capsid-binding patterns of pp150 in human and murine cytomegaloviruses using cryoEM, revealing structural differences and functional implications for using MCMV as a model for HCMV.

bioRxiv · Sep 18, 2018 · PreprintMicrobiology