Author

Karen Jin

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron RenbergiD· 1 shared Adam S. HelmsiD· 1 shared Angelica LiniD· 1 shared Annabel YangiD· 1 shared Bo WeniD· 1 shared Brendon M. BakeriD· 1 shared Brianna Ferguson· 1 shared Daniel Richard WahliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Aaron RenbergORCID

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2 papers

Recent·Most cited

Rac1 and CHK1 Converge on Abi-1 to Regulate DNA Repair Dependency and Treatment Response in Human Cancers

Yiheng Huang, Elizabeth C. McCulla, Jihan Park, Annabel Yang, Timothy Jho, Angelica Lin, Jie Xu, Kari Wilder-Romans, Luke D. Hess, Jing Li, Ningning Liang, Ziqing Zhu, Deven Kothari, Karen Jin, Sarah H. Kim, , Weihua Zhou

This study identifies Abi-1-S323 phosphorylation as a biomarker for DNA repair states and treatment response in cancers, showing its role in regulating radiosensitivity through Rac1 and CHK1 signaling.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology

Desmoplakin Haploinsufficiency Underlies Cell-Cell Adhesion Failure in DSP Cardiomyopathy and is Rescued by Transcriptional Activation

Eric D. Smith, Karen Jin, Brianna Ferguson, Yao-Chang Tsan, Samuel J. DePalma, Joshua K. Meisner, Aaron Renberg, Kenneth C Bedi, Sabrina Friedline, Kenneth B. Margulies, Brendon M. Baker, Adam S. Helms

This study shows that DSP haploinsufficiency causes cell-cell adhesion failure in cardiomyopathy and that increasing DSP expression rescues this defect.

bioRxiv · Jun 1, 2025 · PreprintGenetics