Author

Kate Jeffrey

Wellcome Centre for Cell Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Dhanya K. CheerambathuriD· 2 shared Amy H. BuckiD· 1 shared Andrea GraziadeiiD· 1 shared Atlanta G. CookiD· 1 shared Ayşe Berçin BarlasiD· 1 shared Bram PrevoiD· 1 shared Christian M. T. SpahniD· 1 shared Daniel-Cosmin MarcuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Dhanya K. CheerambathurORCID

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2 papers

Recent·Most cited

An NADH-controlled gatekeeper of ATP synthase

Fabian Schildhauer, Petra S. J. Ryl, Simon Malte Lauer, Swantje Lenz, Ayşe Berçin Barlas, Vasileios R. Ouzounidis, Kate Jeffrey, Daniel-Cosmin Marcu, Francis J. O’Reilly, Andrea Graziadei, Marchel Stuiver, Kita Schmidt, Helge Ewers, Christian M. T. Spahn, Ezgi Karaca, , Juri Rappsilber

The paper identifies AIFM1/AK2 interaction as a gatekeeper of mitochondrial ATP synthase, showing it is NADH-dependent and linked to metabolic state, with implications for mitochondrial diseases.

Molecular Cell · Jun 26, 2025Peer-reviewedBiochemistry

SID-2 localises to extracellular vesicles in parasitic nematodes and does not function in environmental RNAi

Frances Blow, Kate Jeffrey, Franklin Wang‐Ngai Chow, Inna A. Nikonorova, Maureen M. Barr, Atlanta G. Cook, Bram Prevo, Dhanya K. Cheerambathur, Amy H. Buck

This study identifies SID-2 as an extracellular vesicle protein in parasitic nematodes that does not function in environmental RNAi, suggesting a shift in its ancestral role.

Open Biology · Nov 1, 2024Peer-reviewedEvolutionary Biology