The ataxia-telangiectasia disease protein ATM controls vesicular protein secretion via CHGA and microtubule dynamics via CRMP5
Marina Reichlmeir, Ruth Pia Duecker, Hanna Röhrich, Jana Key, Ralf Schubert, Kathryn Abell, Anthony P. Possemato, Matthew P. Stokes, Georg W. J. Auburger
This study identifies ATM's role in regulating vesicular protein secretion through CHGA and microtubule dynamics via CRMP5 in neurons, linking A-T neural atrophy to growth cone collapse.
Neurobiology of Disease · Nov 28, 2024Peer-reviewedCell Biology