Author

Kelly Yichen Li

Sanford Burnham Prebys Medical Discovery Institute

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Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Aaron P. HavasiD· 2 shared Adarsh RajeshiD· 2 shared Alessandra SaccoiD· 2 shared Allen WangiD· 2 shared Andrew Davis· 2 shared Angela LiouiD· 2 shared Armin GandhiiD· 2 shared Bing ReniD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Aaron P. HavasORCID

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2 papers

Recent·Most cited

Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline

Adarsh Rajesh, Aaron P. Havas, Rouven Arnold, Kathryn Lande, Xue Lei, Kelly Yichen Li, Armin Gandhi, Ana Catarina Franco, Seung‐Hwa Woo, Anthony B. Lagnado, Angela Liou, K. Garrett Evensen, Linshan Laux, Maggie Klaers, Jake Kircher, , Peter D. Adams

This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.

Nature Aging · Aug 20, 2026Peer-reviewedCell Biology

Aging-induced hepatocyte CD44 drives IL6/STAT3 signaling and associates with impaired neighboring T cell function.

Armin Gandhi, Kathryn Lande, Kelly Yichen Li, Filipe Araujo Hoffmann, Michael LaPorte, Shirong Tan, K. Garrett Evensen, Benji Portillo, Marcos G. Teneche, Rouven Arnold, Adarsh Rajesh, Jessica Proulx, Shanshan Yin, Aaron P. Havas, Angela Liou, , Peter D. Adams

This study shows that aging-induced CD44 in hepatocytes activates the IL6/JAK/STAT3 pathway, leading to impaired T cell function in the liver.

npj Aging · Aug 13, 2026Peer-reviewedCell Biology