Author

Kezhong Zhang

The Barbara Ann Karmanos Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandro Ponce· 1 shared Alexis Wilson· 1 shared Bo YangiD· 1 shared Charles S. ChungiD· 1 shared Clair Li· 1 shared Daniel XieiD· 1 shared Dogukan Mizrak· 1 shared Donghong JuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Alejandro Ponce

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2 papers

Recent·Most cited

A Marfan-Associated FBN1 Nonsense Mutation Mouse Model Reveals Adventitial Inflammation During Aneurysm Progression

Shichao Wu, Jiawei Zhao, Alejandro Ponce, Lucynda Pham, Daniel Xie, Donghong Ju, Shuping Yin, Francis Hernandez, Sean Jones, Clair Li, Charles S. Chung, Dragana Komnenov, Noreen F. Rossi, Dogukan Mizrak, Bo Yang, , Li Li

This paper develops a mouse model with a FBN1 nonsense mutation to study aneurysm progression, finding that adventitial inflammation contributes to aortic aneurysm rupture.

bioRxiv · Sep 23, 2025 · PreprintGenetics

Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response

Gioia Heravi, Zhenjie Liu, Mackenzie K. Herroon, Alexis Wilson, Yang-Yi Fan, Yang Jiang, Nivisa Vakeesan, Tao Li, Zheyun Peng, Kezhong Zhang, Jing Li, Robert S. Chapkin, Izabela Podgorski, Wanqing Liu

This study shows that inhibiting FADS1 reduces renal cancer growth by inducing ER stress and ATF3-mediated responses, highlighting FADS1 as a therapeutic target.

Biomedicine & Pharmacotherapy · Mar 23, 2025Peer-reviewedCancer Biology