Author

V. Kleshchevnikov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:spatial transcriptomics· 4 Approach:deep learning· 3 Research Focus:spatial domain detection· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

K. Polanski· 3 shared C. Suo· 2 shared E. Dann· 2 shared E. Prigmore· 2 shared E. Stephenson· 2 shared E. Tuck· 2 shared J. C. Marioni· 2 shared J. Engelbert· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

K. Polanski

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Author profile →

4 papers

Recent·Most cited

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Mapping the developing human immune system across organs

C. Suo, E. Dann, I. Goh, L. Jardine, V. Kleshchevnikov, J.-E. Park, R. A. Botting, E. Stephenson, J. Engelbert, Z. K. Tuong, K. Polanski, N. Yayon, C. Xu, O. Suchanek, R. Elmentaite, , S. A. Teichmann

This study maps the developing human immune system across organs using single-cell RNA sequencing, antigen-receptor sequencing, and spatial transcriptomics, revealing cross-gestation and cross-organ variability and identifying prenatal B1 cells and unconventional T cell origins.

bioRxiv · Jan 17, 2022Immunology

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

E. Madissoon, A. J. Oliver, V. Kleshchevnikov, A. Wilbrey-Clark, K. Polanski, A. E. Ribeiro Orsi, L. Mamanova, L. Bolt, J. P. Pett, N. Huang, R. Elmentaite, N. Richoz, P. He, M. Dabrowska, E. Tuck, , K. B. Meyer

The paper creates a spatial multi-omics lung atlas identifying novel cell types and a survival niche for IgA-secreting plasma cells in submucosal glands.

bioRxiv · Nov 26, 2021 · PreprintCell Biology

Spatial genomics maps the structure, character and evolution of cancer clones

A. Lomakin, J. Svedlund, C. Strell, M. Gataric, A. Shmatko, J. S. Park, Y. S. Ju, S. Dentro, V. Kleshchevnikov, V. Vaskivskyi, T. Li, O. A. Bayraktar, L. Moore, S. Pinder, A. L. Richardson, , L. R. Yates

The paper develops a spatial genomics method to map cancer clone structure, character, and evolution across breast cancer progression stages.

bioRxiv · Apr 16, 2021 · PreprintCancer Biology