Author

L. C. Alonso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. B. Sharma· 2 shared A. Bautista· 1 shared B. Gablaski· 1 shared C. Cras-Meneur· 1 shared C. Darko· 1 shared C. E. Ellis· 1 shared C. Nislow· 1 shared D. A. Dionne· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

R. B. Sharma

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2 papers

Recent·Most cited

Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting beta cell differentiation

R. E. Stamateris, R. B. Sharma, H. V. Landa-Galvan, C. Darko, D. Redmond, S. G. Rane, L. C. Alonso

This study shows that CDK4-R24C rescues beta cell mass and dedifferentiation in Irs2-deficient mice by inhibiting FOXO1-mediated repression of Pdx1, independent of insulin sensitivity.

bioRxiv · Oct 19, 2022 · PreprintCell Biology

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

S. Skovso, E. Panzhinskiy, J. Kolic, H. H. Cen, D. A. Dionne, X.-Q. Dai, R. B. Sharma, L. Elghazi, C. E. Ellis, K. Faulkner, S. A. M. Marcil, P. Overby, N. Noursadeghi, D. Hutchinson, X. Hu, , J. D. Johnson

This study shows that deleting the insulin receptor in beta-cells improves glucose tolerance in some mice but not others, depending on age and diet.

bioRxiv · Oct 15, 2020Physiology