Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling
K. H. Mak, Q. Zhao, P.-W. Hu, C.-L. Au-Yeung, J. Yang, L. Duraine, Y. Yu, M. Abu-Remaileh, D. Sabatini, J. Wang, M. C. Wang
This study identifies RSH-1 as a lysosomal NADPH phosphatase that regulates ER proteostasis via mTOR signaling in C. elegans.
bioRxiv · Apr 18, 2020 · PreprintCell Biology