Author

L. E. Cressey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Kettenbach· 1 shared A. N. Kettenbach· 1 shared B. Lopez Mendez· 1 shared B. Rymarczyk· 1 shared E. C. Greiner· 1 shared E. P. Hertz· 1 shared I. Nasa· 1 shared J. Duro· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Kettenbach

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Author profile →

2 papers

Recent·Most cited

Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation

S. P. Lyons, E. C. Greiner, L. E. Cressey, M. E. Adamo, A. N. Kettenbach

This study investigates how C-terminal methylation regulates PP2A, PP4, and PP6 holoenzyme assembly using proteomics and genetic approaches, revealing methylation-dependent interactions in cancer and non-transformed cells.

bioRxiv · Nov 7, 2021Biochemistry

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

S. M. Ambjoern, J. P. Duxin, E. P. Hertz, I. Nasa, J. Duro, T. Kruse, B. Lopez Mendez, B. Rymarczyk, L. E. Cressey, T. Hansen, A. Kettenbach, V. H. Oestergaard, M. Lisby, J. Nilsson

This study identifies the BRCA2-PP2A-B56 complex as essential for efficient DNA repair by homologous recombination and shows that cancer mutations disrupt this interaction, increasing sensitivity to PARP inhibition.

bioRxiv · Apr 10, 2021Cell Biology