Author

V. H. Oestergaard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Nilsson· 2 shared M. Lisby· 2 shared A. Kettenbach· 1 shared A. Stein· 1 shared B. Lopez Mendez· 1 shared B. Rymarczyk· 1 shared D. M. Fowler· 1 shared E. P. Hertz· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

J. Nilsson

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Author profile →

3 papers

Recent·Most cited

A mutational atlas for Parkin proteostasis

L. Clausen, V. Voutsinos, M. Cagiada, K. E. Johansson, M. Gronbaek-Thygesen, S. Nariya, R. L. Powell, M. K. Have, V. H. Oestergaard, A. Stein, D. M. Fowler, K. Lindorff-Larsen, R. Hartmann-Petersen

This study maps Parkin missense variants' abundance and degradation mechanisms, showing most low-abundance variants are degraded via the ubiquitin-proteasome system and stabilized at lower temperatures.

bioRxiv · Jun 8, 2023Biochemistry

A conserved PLK1 docking site in TopBP1 maintains genome integrity during mitosis

J. Li, J. V. Bagge, M. Lisby, J. Nilsson, V. H. Oestergaard

This study identifies a conserved PLK1 docking site in TopBP1 that is essential for maintaining genome integrity during mitosis, as its deletion increases DNA damage and mitotic errors.

bioRxiv · Mar 30, 2022 · PreprintCell Biology

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

S. M. Ambjoern, J. P. Duxin, E. P. Hertz, I. Nasa, J. Duro, T. Kruse, B. Lopez Mendez, B. Rymarczyk, L. E. Cressey, T. Hansen, A. Kettenbach, V. H. Oestergaard, M. Lisby, J. Nilsson

This study identifies the BRCA2-PP2A-B56 complex as essential for efficient DNA repair by homologous recombination and shows that cancer mutations disrupt this interaction, increasing sensitivity to PARP inhibition.

bioRxiv · Apr 10, 2021Cell Biology