Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
M. Paquette, L. El-Houjeiri, L. C. Zirden…·A. Pause
This study shows that AMPK-dependent phosphorylation of TFEB/TFE3 enhances their transcriptional activity under nutrient starvation and promotes chemoresistance in cancer.
M. Paquette, M. Yan, L. El-Houjeiri…·A. Pause
This study shows that FLCN gene ablation reduces fibrosis and inflammation in a diet-induced NASH model by enhancing autophagy and lysosomal biogenesis.
L. El-Houjeiri, E. Possik, T. Tarika Vijayaraghavan…·A. Pause
This study identifies a conserved mechanism linking FLCN-AMPK signaling to TFEB/TFE3 activation, enhancing innate immunity and pathogen resistance across species.