L. Gay

Warnings/Cautions when collecting Brassica diversity along a large climatic gradient

The paper warns about misidentification issues in collecting Brassica species along a climatic gradient and reports findings on genetic diversity and misidentified populations.

Vγ9Vδ2 T cells are potent inhibitors of SARS-CoV-2 replication and exert effector phenotypes in COVID-19 patients

This paper investigates how SARS-CoV-2 affects Vγ9Vδ2 T cells in patients and shows that anti-BTN3A activation enhances their antiviral response.

Laboratory Yeast Strains Rely On Oxidative Phosphorylation For Efficient ATP Production

The paper shows that the lab yeast strain SEY6210 relies on oxidative phosphorylation for efficient ATP production, even at high glucose concentrations.

Identity and provenance of neighbors, genotype-specific traits and abiotic stress affect intraspecific interactions in the annual legume Medicago truncatula

The paper investigates how genotype-specific traits, abiotic stress, and neighbor identity influence intraspecific interactions in Medicago truncatula, finding that non-kin neighbors promote growth more than kin under low stress.

Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis

This study shows SARS-CoV-2 infects monocytes and macrophages, inducing immunoregulatory cytokine secretion and M2-type transcriptional changes, leading to immunoparalysis in Covid-19 patients.

Daytime variation in SARS-CoV-2 infection and cytokine production

This study shows that SARS-CoV-2 infection and cytokine production in human monocytes vary with the time of day, suggesting circadian rhythm influences viral progression and immune response.

Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift

The paper uses a resurrection study to analyze flowering time evolution in a selfing Medicago truncatula population, finding evidence of adaptation but also suggesting drift could explain the observed changes.

Power and limits of selection genome scans on temporal data from a selfing population

The paper evaluates the power of selection scans in selfing populations and finds that detecting selection remains challenging despite method adaptations.

Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer

This study analyzes longitudinal genomic data from colorectal cancer patients to show that negative selection stabilizes karyotypes during tumor progression and metastasis.

PDGFRA Defines the Mesenchymal Stem Cell Kaposi’s Sarcoma Progenitors by Enabling KSHV Oncogenesis in an Angiogenic Environment

The paper identifies PDGFRA+ bone marrow-derived mesenchymal stem cells as Kaposi’s sarcoma progenitors and shows pro-angiogenic conditions enable KSHV oncogenesis through epigenetic de-repression.

Discontinuities in quinoa biodiversity in the dry Andes: an 18-century perspective based on allelic genotyping

This study tracks changes in quinoa genetic diversity over 18 centuries using ancient DNA and genotyping, revealing gene pool replacements linked to agricultural and environmental changes.