Author

L. H. Chu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Oberst· 2 shared B. P. Daniels· 1 shared D. M. Marciniak· 1 shared J. M. Ames· 1 shared K. Lichauco· 1 shared K. Somfleth· 1 shared M. G. Thompson· 1 shared M. Gale· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. Oberst

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons

S. B. Kofman, L. H. Chu, J. M. Ames, S. D. Chavarria, K. Lichauco, B. P. Daniels, A. Oberst

This study shows RIPK3 drives antiviral transcription in neurons during ZIKV infection, while inducing cell death in MEFs, with RHIM domain interactions mediating these context-dependent functions.

bioRxiv · Feb 29, 2024 · PreprintImmunology

Cellular RNA interacts with MAVS to promote antiviral signaling

N. S. Gokhale, K. Somfleth, M. G. Thompson, R. K. Sam, D. M. Marciniak, L. H. Chu, M. Park, S. Dvorkin, A. Oberst, S. M. Horner, S.-E. Ong, M. Gale, R. Savan

The paper shows that cellular RNA interacts with MAVS to scaffold signaling proteins and promote antiviral signaling by facilitating IRF3 phosphorylation.

bioRxiv · Sep 25, 2023 · PreprintImmunology