Author

L. Halasz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Debraekeleer· 1 shared A. J. Kaufman· 1 shared A. M. Tsankov· 1 shared A. Magen· 1 shared A. Marks· 1 shared B. D. Brown· 1 shared B. Daniel· 1 shared B. Giotti· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Debraekeleer

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2 papers

Recent·Most cited

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors

S. Hegde, B. Giotti, B. Y. Soong, L. Halasz, J. Le Berichel, A. Magen, B. Kloeckner, R. Mattiuz, M. D. Park, A. Marks, M. Belabed, P. Hamon, T. Chin, L. Troncoso, J. J. Lee, , M. Merad

The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.

bioRxiv · Jun 24, 2024Immunology

Epigenomic programming of peripheral monocytes determines their transcriptional response to the tumor microenvironment

M. Kiss, L. Halasz, E. Hadadi, W. K. Berger, P. Tzerpos, S. Poliska, D. Kancheva, A. Debraekeleer, J. Brughmans, Y. Elkrim, L. Martens, Y. Saeys, B. Daniel, Z. Czimmerer, D. Laoui, , J. A. Van Ginderachter

This study shows that peripheral monocytes' epigenomic landscape is rewired by a distal tumor, shaping their transcriptional response upon tumor infiltration.

bioRxiv · Jun 19, 2024Immunology