Author

D. Kancheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Debraekeleer· 2 shared D. Laoui· 2 shared E. Hadadi· 2 shared J. Brughmans· 2 shared K. Movahedi· 2 shared M. Kiss· 2 shared Y. Elkrim· 2 shared A. D. Garg· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Debraekeleer

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Epigenomic programming of peripheral monocytes determines their transcriptional response to the tumor microenvironment

M. Kiss, L. Halasz, E. Hadadi, W. K. Berger, P. Tzerpos, S. Poliska, D. Kancheva, A. Debraekeleer, J. Brughmans, Y. Elkrim, L. Martens, Y. Saeys, B. Daniel, Z. Czimmerer, D. Laoui, , J. A. Van Ginderachter

This study shows that peripheral monocytes' epigenomic landscape is rewired by a distal tumor, shaping their transcriptional response upon tumor infiltration.

bioRxiv · Jun 19, 2024Immunology

Murine GMP- and MDP-derived classical monocytes have distinct functions and fates

S. Trzebanski, J.-S. Kim, N. Larrossi, D. Kancheva, J. Bastos, M. Haddad, D. Aizik, J. Kralova, M. Gross-Vered, S. Boura-Halfon, T. Lapidot, R. Alon, K. Movahedi, S. Jung, E. Sivan, , A. Raanan

This study identifies distinct functions and fates of murine classical monocytes derived from GMP and MDP, showing differential contributions to tissue macrophage populations.

bioRxiv · Jul 29, 2023Immunology

Global hypo-methylation in a subgroup of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

J. Boot, G. Rosser, D. Kancheva, C. Vinel, Y. M. Lim, N. Pomella, X. Zhang, L. Guglielmi, D. Sheer, M. Barnes, S. Brandner, S. Nelander, K. Movahedi, S. Marino

The paper identifies a glioblastoma subgroup with global hypo-methylation and astrocytic features linked to invasion and immune changes.

bioRxiv · Feb 15, 2022 · PreprintCancer Biology

Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy

A. Murgaski, M. Kiss, H. Van Damme, D. Kancheva, I. Vanmeerbeek, J. Keirsse, E. Hadadi, J. Brughmans, S. M. Arnouk, A. E. I. Hamouda, A. Debraekeleer, V. Bosteels, Y. Elkrim, L. Boon, S. Hoves, , D. Laoui

This study identifies cDC subsets that cooperate in CD40 agonist response and shows that suppressive microenvironments and antigen scarcity limit its efficacy in cancer.

bioRxiv · Dec 25, 2021 · PreprintCancer Biology