J. Deschamps

Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology

This study identifies monoclonal antibodies targeting C. difficile's S-layer protein, revealing both protective and detrimental effects on bacterial physiology.

Bile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump

This paper identifies a bile-induced RND efflux pump in Bacteroides thetaiotaomicron that facilitates magnesium efflux, reducing eDNA concentration and promoting biofilm formation.

Multi-scale transcriptome unveils spatial organisation and temporal dynamics of Bacillus subtilis biofilms

This study uses RNA-seq and time-lapse microscopy to analyze spatial and temporal gene expression in Bacillus subtilis biofilms, revealing mosaic gene expression patterns and spatially segregated metabolic states.

Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile

This study shows that extracellular succinate induces biofilm formation in C. difficile, leading to thicker, more complex biofilms associated with infection relapse.

MicroFPGA: an affordable FPGA platform for microscope control

MicroFPGA provides an affordable FPGA-based platform for microscope control, enabling high-speed and parallel processing of complex control tasks.

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation

This study identifies bile as a trigger for biofilm formation in Bacteroides thetaiotaomicron and shows that extracellular DNA degradation by DNase BT3563 is essential for this process.

Photon-free (s)CMOS camera characterization for artifact reduction in high- and super-resolution microscopy

This paper develops an automated pipeline for sCMOS camera characterization using thermal signals, enabling artifact reduction in high- and super-resolution microscopy without additional hardware or user intervention.

Direct Supercritical Angle Localization Microscopy for Nanometer 3D Superresolution

This paper introduces SALM, a 3D superresolution technique that improves z-resolution by four times using direct splitting of supercritical and undercritical emission.

A cost-efficient open source laser engine for microscopy

The paper presents an open-source, cost-efficient laser engine for microscopy using affordable diodes and fiber delivery to reduce speckles.

Systematic analysis of the molecular architecture of endocytosis reveals a nanoscale actin nucleation template that drives efficient vesicle formation

The paper uses high-throughput superresolution microscopy to analyze endocytic protein organization in yeast, revealing a WASP nano-template that enhances actin nucleation efficiency during vesicle formation.