Author

R. Briandet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Deschamps· 5 shared B. Dupuy· 3 shared A.-A. LOPES· 2 shared E. Auria· 2 shared J.-M. GHIGO· 2 shared A. Combeau· 1 shared B. Iannascoli· 1 shared C. Deneve-Larrazet· 1 shared

Activity by Year

2021-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

J. Deschamps

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology

L. Hunault, E. Auria, P. England, J. Deschamps, R. Briandet, V. Kremer, B. Iannascoli, L. Vidal-Maison, C. Guo, L. Macdonald, S. Pechine, C. Deneve-Larrazet, B. Dupuy, G. Gorochov, P. Bruhns, D. Sterlin

This study identifies monoclonal antibodies targeting C. difficile's S-layer protein, revealing both protective and detrimental effects on bacterial physiology.

bioRxiv · Sep 21, 2023 · PreprintMicrobiology

Bile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump

A.-A. LOPES, J. DESCHAMPS, S. GEORGEAULT, T. COKELAER, R. BRIANDET, J.-M. GHIGO

This paper identifies a bile-induced RND efflux pump in Bacteroides thetaiotaomicron that facilitates magnesium efflux, reducing eDNA concentration and promoting biofilm formation.

bioRxiv · Jul 26, 2023 · PreprintMicrobiology

Spatially localized expression of glutamate decarboxylase gadB in Escherichia coli O157:H7 microcolonies in hydrogel matrix

C. Saint Martin, N. Caccia, M. Darsonval, M. Gregoire, A. Combeau, G. Jubelin, F. Dubois-Brissonnet, S. Leroy, R. Briandet, M. Desvaux

The paper visualizes spatial gadB expression in E. coli O157:H7 microcolonies and shows its role in acid tolerance.

bioRxiv · Feb 16, 2023 · PreprintMicrobiology

Multi-scale transcriptome unveils spatial organisation and temporal dynamics of Bacillus subtilis biofilms

Y. Dergham, D. Le Coq, P. Nicolas, J. Deschamps, E. Huillet, P. Sanchez-Vizuete, K. Hamze, R. Briandet

This study uses RNA-seq and time-lapse microscopy to analyze spatial and temporal gene expression in Bacillus subtilis biofilms, revealing mosaic gene expression patterns and spatially segregated metabolic states.

bioRxiv · Jan 6, 2023 · PreprintMicrobiology

Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile

E. Auria, J. Deschamps, R. Briandet, B. Dupuy

This study shows that extracellular succinate induces biofilm formation in C. difficile, leading to thicker, more complex biofilms associated with infection relapse.

bioRxiv · Jan 2, 2023 · PreprintMicrobiology

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation

N. BECHON, J. MIHAJLOVIC, A.-A. LOPES, S. VENDRELL-FERNANDEZ, J. DESCHAMPS, R. BRIANDET, O. SISMEIRO, I. MARTIN-VERSTRAETE, B. DUPUY, J.-M. GHIGO

This study identifies bile as a trigger for biofilm formation in Bacteroides thetaiotaomicron and shows that extracellular DNA degradation by DNase BT3563 is essential for this process.

bioRxiv · Jun 4, 2021Microbiology