E. Cappio Barazzone

Targeted induction of gut-microbial metabolism acutely affects feeding patterns and clock gene expression in the host

This study shows that increasing gut microbial metabolism in mice affects host clock gene expression and reduces food intake beyond microbial calorie contribution.

A rationally designed inactivated Salmonella Typhimurium vaccine induces strong and long-lasting immune responses in pigs

This study evaluates an inactivated Salmonella Typhimurium vaccine in pigs, showing strong and long-lasting immune responses with improved safety and seroconversion compared to live vaccines.

Vaccine-enhanced competition permits rational bacterial strain replacement in the gut

The paper demonstrates that oral vaccination combined with engineered competitor strains can exclude pathogens and replace bacterial strains in the mouse gut.

Metabolic reconstitution by a gnotobiotic microbiota varies over the circadian cycle

This study shows that a gnotobiotic microbiota affects metabolic processes differently depending on the circadian cycle, influencing energy balance and substrate utilization.

ultraID: a compact and efficient enzyme for proximity-dependent biotinylation in living cells

The paper introduces ultraID, a compact and efficient biotin ligase for proximity-dependent biotinylation, demonstrating its use in probing interactomes with high temporal resolution.