Author

V. Lentsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Slack· 4 shared C. Loverdo· 2 shared C. Moresi· 2 shared D. Hoces· 2 shared E. Cappio Barazzone· 2 shared M. Diard· 2 shared R. Mezzenga· 2 shared S. Aslani· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersImmunology

E. Slack

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Surface crosslinking of virus-like particles increases resistance to proteases, low pH and mechanical stress for mucosal applications

A. Ali, S. Ganguillet, Y. Turgay, T. Keys, E. Causa, R. Fradique, V. Lutz-Bueno, S. Chesnov, C.-W. Lin, V. Lentsch, J. Kotar, P. Cicuta, R. Mezzenga, E. Slack, M. Radiom

This study enhances the stability of virus-like particles (VLPs) against environmental stressors by surface crosslinking, without affecting their vaccine function.

bioRxiv · Jul 29, 2023 · PreprintBiophysics

A rationally designed inactivated Salmonella Typhimurium vaccine induces strong and long-lasting immune responses in pigs

V. Lentsch, S. Aslani, T. Echtermann, S. Preet, E. Cappio Barazzone, D. Hoces, C. Moresi, D. Kuemmerlen, E. Slack

This study evaluates an inactivated Salmonella Typhimurium vaccine in pigs, showing strong and long-lasting immune responses with improved safety and seroconversion compared to live vaccines.

bioRxiv · Mar 27, 2023Immunology

Vaccine-enhanced competition permits rational bacterial strain replacement in the gut

V. Lentsch, A. Woller, A. Rocker, S. Aslani, C. Moresi, N. Ruoho, L. Larsson, S. A. Fattinger, N. Wenner, E. Cappio Barazzone, W.-D. Hardt, C. Loverdo, M. Diard, E. Slack

The paper demonstrates that oral vaccination combined with engineered competitor strains can exclude pathogens and replace bacterial strains in the mouse gut.

bioRxiv · Jul 20, 2022Microbiology

A rationally designed oral vaccine induces Immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

M. Diard, E. Bakkeren, D. Hoces, V. Lentsch, M. Arnoldini, F. Boehi, K. Schumann-Moor, J. Adamcik, L. Piccoli, A. Lanzavecchia, B. Stadtmueller, N. Donohue, M. Vanderwoude, P. Viollier, L. Falquet, , E. Slack

This paper shows that an oral vaccine inducing IgA in mice can direct Salmonella to evolve into less virulent variants with shorter O-antigens.

bioRxiv · May 13, 2021Immunology