Author

A. P. Bowman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:metabolomics· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

C. C. Nelson· 2 shared K. D. Tousignant· 2 shared R. M. A. Heeren· 2 shared R. S. E. Young· 2 shared S. Ellis· 2 shared S. J. Blanksby· 2 shared B. L. J. Poad· 1 shared B. L. Poad· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

C. C. Nelson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Isomeric lipid signatures reveal compartmentalised fatty acid metabolism in cancer

R. S. E. Young, A. P. Bowman, K. D. Tousignant, B. L. J. Poad, J. H. Gunter, L. K. Philp, C. C. Nelson, S. Ellis, R. M. A. Heeren, M. C. Sadowski, S. J. Blanksby

This study uses stable-isotope labelled fatty acids to reveal distinct metabolic fates of exogenous and de novo synthesized fatty acids in cancer cells, showing compartmentalized lipid metabolism.

bioRxiv · Nov 1, 2021 · PreprintCancer Biology

Sphingolipid Control of Fibroblast Heterogeneity Revealed by Single-Cell Lipidomics

L. Capolupo, I. Khven, L. Mazzeo, G. Glousker, F. Russo, J. Paz Montoya, S. Ho, D. R. Bhandari, A. P. Bowman, S. Ellis, R. Guiet, J. Muthing, B. Spengler, R. M. A. Heeren, G.-P. Dotto, , G. D'Angelo

This study identifies sphingolipid composition as a driver of fibroblast heterogeneity and state transitions using single-cell lipidomics and transcriptomics.

bioRxiv · Feb 23, 2021 · PreprintBiochemistry

Metabolic plasticity in cancer activates apocryphal pathways for lipid desaturation

R. S. E. Young, A. P. Bowman, E. D. Williams, K. D. Tousignant, C. L. Bidgood, V. R. Narreddula, R. Gupta, D. L. Marshall, B. L. Poad, C. C. Nelson, S. R. Ellis, R. M. Heeren, M. Sadowski, S. J. Blanksby

The paper reveals metabolic plasticity in cancer through isomer-resolved lipidomics, identifying apocryphal pathways for lipid desaturation and their impact on lipid structure and function.

bioRxiv · Jun 7, 2020 · PreprintBiochemistry