Author

L. Nezi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. B. Nava Lauson· 2 shared S. Tiberti· 2 shared A. D. Macandog· 1 shared A. Mukherjee· 1 shared A. O. Bigogno· 1 shared C. Catozzi· 1 shared C. Scirgolea· 1 shared C. Soriani· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

C. B. Nava Lauson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.

I. Pallavicini, T. M. Frasconi, E. Ceccaci, S. Tiberti, C. B. Nava Lauson, E. Preto, A. O. Bigogno, M. Mangione, E. Sala, M. Iannacone, M. Kuka, L. Nezi, S. Minucci, T. Manzo

This study shows that inhibiting LSD1 enhances CD8+ T cell function in adoptive T cell therapy, leading to improved antitumor immunity and synergistic effects with anti-PDL1 therapy.

bioRxiv · Oct 27, 2023Immunology

Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

A. Mukherjee, D. Bezwada, M. Zandbergen, F. Francesco Greco, C.-Y. Chiang, M. Tasdemir, J. Fahrmann, D. Grapov, M. R. La Frano, H. S. Vu, J. W. Newman, L. A. McDonnell, L. Nezi, O. Fiehn, R. J. DeBerardinis, E. Lengyel

This study shows adipocytes reprogram cancer cell glucose metabolism to promote metastasis by increasing lipid synthesis via HIF1 regulation.

bioRxiv · Oct 17, 2022 · PreprintCancer Biology

GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome.

S. Tiberti, C. Catozzi, C. Scirgolea, O. Croci, M. Ballerini, D. Cagnina, C. Soriani, A. D. Macandog, C. B. Nava Lauson, G. Bertalot, W. L. Petz, S. P. Ravenda, V. Licursi, P. Paci, M. Rasponi, , T. o. MANZO

The paper identifies GZMKhigh CD8+ T effector memory cells in early-stage CRC tumors, which correlate with neutrophil abundance and predict poor clinical outcomes.

bioRxiv · Dec 14, 2021Immunology