Author

C. Soriani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. R. Ippolito· 2 shared S. Santaguida· 2 shared A. Castiglioni· 1 shared A. D. Macandog· 1 shared A. Davis· 1 shared A. Dondi· 1 shared A. E. Tijhuis· 1 shared A. Farfalla· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

M. R. Ippolito

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Automated workflow for the cell cycle analysis of non-adherent and adherent cells using a machine learning approach

K. Hayatigolkhatmi, C. Soriani, E. Soda, E. Ceccacci, O. El Menna, S. Peri, I. Negrelli, G. Bertolini, G. M. Franchi, R. Carbone, S. Minucci, S. Rodighiero

This paper introduces an automated method for analyzing the cell cycle in both adherent and non-adherent cells using machine learning, validated in AML cell lines and drug response testing.

bioRxiv · Dec 21, 2023Cell Biology

NF1 modulates microtubule repair and sensitivity to antibody-drug conjugates

B. Achutti Duso, E. Messuti, G. Tini, E. Bonetti, A. Castiglioni, G. Frige, G. Ciossani, S. Monzani, C. Soriani, D. Khuntsariya, N. Roda, A. Polazzi, M. R. Ippolito, E. Gavilan Dorronzoro, E. Mane, , L. Mazzarella

This study shows that NF1 loss increases sensitivity to the ADC T-DM1 by modulating microtubule repair and dynamics, identifying NF1 as a predictive biomarker for ADC response.

bioRxiv · Dec 6, 2023 · PreprintCancer Biology

Short-term molecular consequences of chromosome mis-segregation for genome stability

L. Garribba, G. De Feudis, V. Martis, M. Galli, M. Dumont, Y. Eliezer, R. Wardenaar, M. R. Ippolito, D. R. Iyer, A. E. Tijhuis, D. C. Spierings, M. Schubert, S. Taglietti, C. Soriani, S. Gemble, , S. Santaguida

This study shows that aneuploidy can trigger chromosome instability (CIN) by causing DNA replication stress and continuous CIN, leading to genetically diverse cells with varying proliferation abilities.

bioRxiv · Jun 19, 2022Cell Biology

GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome.

S. Tiberti, C. Catozzi, C. Scirgolea, O. Croci, M. Ballerini, D. Cagnina, C. Soriani, A. D. Macandog, C. B. Nava Lauson, G. Bertalot, W. L. Petz, S. P. Ravenda, V. Licursi, P. Paci, M. Rasponi, , T. o. MANZO

The paper identifies GZMKhigh CD8+ T effector memory cells in early-stage CRC tumors, which correlate with neutrophil abundance and predict poor clinical outcomes.

bioRxiv · Dec 14, 2021Immunology

Criticality of plasma membrane lipids reflects activation state of macrophage cells

E. Cammarota, C. Soriani, R. Taub, F. Morgan, J. Sakai, S. Veatch, C. E. Bryant, P. Cicuta

The paper examines how macrophage plasma membrane lipid composition changes in response to inflammatory stimuli, showing that proximity to a critical point affects membrane protein activity.

bioRxiv · Jun 23, 2019Biophysics