Author

L. R. Leddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Andrews· 1 shared B. P. Riesenberg· 1 shared C. M. Paulos· 1 shared D. M. Neskey· 1 shared E. G. Hill· 1 shared E. G. Hunt· 1 shared G. O. R. Rivera· 1 shared J. E. Thaxton· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. M. Andrews

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1 paper

Recent·Most cited

Stress-Mediated Attenuation of Translation Undermines T Cell Tumor Control

B. P. Riesenberg, E. G. Hunt, M. D. Tennant, K. E. Hurst, A. M. Andrews, L. R. Leddy, D. M. Neskey, E. G. Hill, G. O. R. Rivera, C. M. Paulos, P. Gao, J. E. Thaxton

This study shows that solid tumor microenvironment stress reduces T cell protein translation via the UPR and p-eIF2, and that proteasome stimulation can reverse this effect to enhance antitumor immunity.

bioRxiv · Jan 31, 2022 · PreprintImmunology